RIDGE REGRESSION AND ITS APPLICATIONS IN GENETIC STUDIES.

Ridge regression and its applications in genetic studies.

With the advancement of technology, analysis of large-scale data of gene expression is feasible and has become very popular in the era of machine learning.This paper develops an improved ridge approach for the genome regression modeling.When multicollinearity exists in the data set with outliers, we consider a robust ridge estimator, namely the ran

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How Transportation Restriction Shapes the Relationship Between Ambient Nitrogen Dioxide and COVID-19 Transmissibility: An Exploratory Analysis

Background: Several recent studies reported a positive (statistical) association between ambient nitrogen dioxide (NO2) and COVID-19 transmissibility.However, considering the intensive transportation restriction due to lockdown measures that would lead to declines in both ambient NO2 concentration and COVID-19 spread, the crude or insufficiently ad

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A Molecular Troika of Angiogenesis, Coagulopathy and Endothelial Dysfunction in the Pathology of Avascular Necrosis of Femoral Head: A Comprehensive Review

Avascular necrosis of the femoral head (ANFH) is a painful disorder characterized by the cessation of blood supply to the femoral head, leading to its death and subsequent joint collapse.Influenced by several risk factors, including corticosteroid use, excessive alcohol intake, hypercholesterolemia, smoking and some inflammatory disorders, along wi

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Titanite Mineralization of Microbial Bioalteration Textures in Jurassic Volcanic Glass, Coast Range Ophiolite, California

Volcanic glasses are rarely preserved in the rock record, and the quality of preservation generally declines with increasing age.Records preserved in ancient basaltic glasses therefore provide important links between processes operating in the distant past, and those that are active on the Earth today.Microbial colonization has been linked to the f

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Peripheral Nervous System Pathways

Abstract This resource is a web-based tutorial aimed at conveying information about the neurons forming the peripheral nervous system and the nomenclature (functional components) used to classify them.The objective was to stimulate self-directed learning by creating animated diagrams summarizing cranial and spinal nerve pathways accompanied by Micr

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